Medical Care
Skyler Andrews: From Augusta to Arts and Beyond
2024-11-30
Skyler Andrews, a remarkable individual with deep roots in the CSRA (Central Savannah River Area), has led a diverse and fulfilling life. Born in Augusta and raised in Aiken, with family ties in Edgefield County, South Carolina, he now calls the Augusta area home. With a Bachelor of Arts in English from the University of South Carolina – Aiken, he has made significant contributions to the world of content creation. He has produced engaging pieces for Verge Magazine, The Aiken Standard, and the Augusta Conventions and Visitors Bureau. While juggling various jobs such as pest control, life insurance, and real estate, he remains actively involved in the Augusta arts community. He writes plays, short stories, and spoken-word pieces, and can often be spotted in downtown Augusta, either with a book in hand, writing, or performing stand-up comedy.

Uncovering the Multifaceted Life of Skyler Andrews in the CSRA

Early Life and Roots

Skyler Andrews' journey began in Augusta, where he was born. Growing up in Aiken, he was surrounded by the charm and culture of the region. His family roots in Edgefield County, South Carolina, added a rich heritage to his life. These early experiences shaped his perspective and laid the foundation for his future endeavors.His connection to the CSRA is not just geographical; it runs deep in his heart and soul. The memories of his childhood in these areas have influenced his work and creative pursuits.

Educational Journey and Career in Content Creation

After graduating from the University of South Carolina – Aiken with a Bachelor of Arts in English, Skyler Andrews embarked on a career in content creation. His skills in writing and storytelling allowed him to produce captivating pieces for various platforms.He has worked with renowned publications like Verge Magazine and The Aiken Standard, leaving his mark with his unique style and perspective. His contributions to the Augusta Conventions and Visitors Bureau have also helped promote the area and its attractions.In addition to his formal education, his real-life experiences in different jobs, such as pest control, life insurance, and real estate, have given him a diverse set of skills and insights. These experiences have enriched his writing and allowed him to connect with a wider audience.

Active Participation in the Augusta Arts Community

Skyler Andrews is not just a writer; he is an active participant in the Augusta arts community. His passion for the arts is evident in his works, whether it's writing plays, short stories, or spoken-word pieces.He can often be found in downtown Augusta, immersed in the creative atmosphere. His nose in a book shows his love for literature, while his writing and performing stand-up comedy demonstrate his artistic talent.His involvement in the arts community has not only brought him personal fulfillment but has also contributed to the cultural fabric of Augusta. He is a source of inspiration for other artists and a driving force in the local arts scene.
Prognostic Models for Young Cervical Cancer: Age Stratification by Restricted Cubic Splines
2024-11-30
Cervical cancer poses a significant global health challenge, with young women being particularly affected. In this study, we aimed to develop and validate prognostic models for young cervical cancer patients. By extracting data from the SEER database and a local hospital database, we conducted a comprehensive analysis.

Unveiling the Prognosis of Young Cervical Cancer Patients with Advanced Models

Age-Stratified Incidence and Outcomes of CC

Our study included 27,658 cases from the SEER database. The restricted cubic spline (RCS) analysis showed a nonlinear relationship between age and cervical cancer-specific mortality. Patients under 36 years old had the lowest risk, while those over 60 had the highest. The Kaplan-Meier curves demonstrated that the young group had the best prognosis, with a 5-year overall survival (OS) and cancer-specific survival (CSS) rate of over 70%.

Baseline Characteristics of Young Group Patients and Differences from the Other Two Groups

Nearly half of the young patients (44.4%) were never married, and a higher proportion had a relatively lower median household income. They showed high treatment compliance, with a higher proportion accepting treatment within 1 month. In terms of clinical characteristics, the young group had a higher proportion of early-stage tumors, smaller tumor sizes, and grade 1 tumors.

Prognostic Factors for Young Cervical Cancer Patients

Using univariate and multivariate Cox regression analyses, we identified pathologic type, FIGO stage, tumor size, and surgery as significant risk factors. Although grade did not meet the p < 0.01 criterion, it was also incorporated due to its recognized importance. Chemotherapy and radiotherapy status were significant high-risk factors but were not included due to potential multicollinearity issues.

Visualization and Validation of the Prognostic Models

Nomograms were developed to visualize the prognostic models. Stage had the greatest impact on prognosis, followed by tumor size. The C-indexes for the OS and CSS prognosis were 0.805 and 0.820, respectively. In the validation cohort from the Guizhou Provincial People's Hospital, the C-index was 0.865, confirming the good predictive ability of the nomograms. The calibration plots also showed a high fit between the nomogram-predicted survival and actual survival.

Comparison of the Nomogram with the FIGO Staging System

The ROC curve comparison showed that our model had higher efficacy in predicting OS than the FIGO staging system (2018). This indicates that our prognostic models, which incorporate additional factors such as pathological type and grade, provide more accurate predictions.

Conclusion

Based on our findings, we defined young cervical cancer as occurring in individuals under 36 years old. The young group had a better prognosis with independent prognostic factors including disease stage, tumor size, grade, histologic type, and surgical intervention. Our prognostic models serve as a valuable supplement to the current FIGO staging system and have good calibration and high accuracy.
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Исторические периоды и их мини-юбки у Голливудских звезд
2024-11-30
Юбки всегда играли важную роль в женском гардеробе. Их мода менялась вместе с эпохами, от строгих классических моделей до свободных и игривых. А эффектные мини-юбки вызывали особый интерес, привлекающие взгляды и создавая вау-эффект.

Теглайн: Мини-Юбки - Символ Свободы и Смелости

80-е годы

В 1980-е годы Мадонна стала истинной иконой стиля, перевернув представление о моде. Она часто носила мини-юбки, которые были яркими, дерзкими и эксцентричными. От кожаных до пестрых, с блестками или в кислотных цветах, она сочетала их с оверсайз-куртками, сетчатыми колготками или кружевными и укороченными топами. Это добавляло в образ нотки панковской провокации и пикантной дерзости.

Мадонна смело смешала разные направления моды, от панка до глэма. Фото: dzen.ru и pinterest.com

90-е годы

Фильм «Красотка» в 90-е годах стал настоящим фурором в мире моды. Мини-юбки и короткие платья перестали быть вульгарными или провокационными, а стали воплощением уверенности и независимости. Джулия Робертс носила их с легкостью, и ее образ стал вдохновением для женщин по всему миру.

Вивиан, главная героиня фильма, выбирала броские вещи яркого цвета, которые показывали ее внутреннюю свободу и готовность идти наперекор стереотипам. Глядя на нее, можно увидеть, что мода - это не только одежда, но и чувство себя в ней. Если вы в своей мини-юбке ощущаете себя как звезда, вы уже ее стали!

Джулия Робертс, сыгравшая Вивиан, воплотила в своем образе баланс между простотой и бунтарством. Фото: dzen.ru и kinopoisk.ru

2000-е годы

В 2000-е годах джинсовые мини-юбки стали настоящим хитом. Они были легкими и стильными, и попали в гардеробы всех модниц. Пэрис Хилтон, Кристина Агилера и Бритни Спирс все носили их на различные мероприятия. Джинсовую мини-юбку обычно сочетали с яркими топами, акцентными ремнями и высокими каблуками.

Кто бы мог подумать, что такой простой элемент одежды станет модным заявлением целого поколения? Фото: pinterest.com и peopletalk.ru

2010-е годы

Латексные мини-юбки стали горячей тенденцией в 2010-е годах. Они идеально подчеркивают фигуру, придавая образу игривость и футуристическое настроение. Носить такую юбку - это значит заявить о себе! Кожаные мини-юбки также добавили нотку рок-н-ролла в моду, но с более утонченным и гламурным подтекстом.

На красных дорожках часто можно увидеть в латексных или кожаных юбках звезды, как Ким Кардашьян, Рианна и Ники Минаж. Это - визитная карточка их смелого стиля!

Ким Кардашьян блистает в смелом латексном мини, а Рианна выбирает дерзкую кожаную юбку. Фото: dzen.ru и pinterest.com

2020-е годы

В 2020-е годы теннисные юбки получили настоящий триумф. Они вышли из спортивных залов и вошли в повседневные гардеробы. Они идеально сочетают комфорт, стиль и нотку ностальгии. В эпоху, когда мода тяготеет к ретро-стилю и спортивному шику, теннисная юбка стала олицетворением свободы и свежести.

Как легко ее комбинировать! От кроп-топов и худи до классических рубашек и жакетов - теннисная юбка всегда выглядит уместно и современно. Белла Хадид и Зендия, знаменитости, которые обожают этот тренд, добавляют еще больше привлекательности.

Зендия и Белла Хадид в стильной теннисной юбке, окруженные фанатами. Фото: pinterest.com и marieclaire.ru

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