A remarkable collaboration between artificial intelligence and biotechnology is underway, aiming to revolutionize the field of longevity science. According to a report from MIT Technology Review, OpenAI has partnered with Retro Biosciences, a startup focused on extending human lifespan by a decade. The two organizations have jointly developed an AI model named GPT-4b micro, which focuses on re-engineering specific proteins known as Yamanaka factors. These proteins play a crucial role in transforming human skin cells into stem cells that exhibit youthful characteristics. This innovative approach holds promise for generating replacement cells and even building human organs, potentially opening new frontiers in medical science.
The partnership between OpenAI and Retro Biosciences has been evolving over the past year, driven by shared goals in advancing biological research. Retro Biosciences, supported by prominent figures such as Sam Altman, has been at the forefront of exploring ways to extend human life. The GPT-4b micro model represents a significant leap forward in this endeavor. Unlike other models like Google’s AlphaFold, which predicts protein structures, GPT-4b micro takes a different approach by focusing on re-engineering proteins. Specifically, it aims to manipulate the Yamanaka factors, which are key to rejuvenating cells. By doing so, the model could pave the way for breakthroughs in regenerative medicine, offering hope for treatments that were previously unimaginable.
This collaboration marks OpenAI's first venture into custom-built AI models designed specifically for biological research. The development of GPT-4b micro highlights the growing intersection between AI and biotechnology, where machine learning can accelerate scientific discovery. The potential applications of this technology are vast, ranging from creating younger cells to developing entirely new organs. Both OpenAI and Retro Biosciences have indicated plans to publish their findings, allowing the broader scientific community to benefit from this groundbreaking work. The release of this research could spur further innovation and collaboration across multiple disciplines, ultimately leading to advancements that may redefine the limits of human health and longevity.
The implications of this joint effort between OpenAI and Retro Biosciences are profound. By leveraging AI to manipulate cellular processes, researchers are inching closer to unlocking the secrets of aging and regeneration. The successful development of GPT-4b micro not only advances the field of longevity science but also demonstrates the power of interdisciplinary collaboration. As more details about the model and its outputs become available, the scientific community will undoubtedly take notice. This collaboration could serve as a catalyst for future research, inspiring new approaches to tackling some of the most pressing challenges in healthcare and extending the boundaries of human potential.
In a recent interview, veteran actor Christopher Walken reminisced about his early days in the entertainment industry and shared anecdotes of working alongside some of Hollywood’s most iconic figures. During an appearance on SiriusXM’s Town Hall hosted by Andy Cohen, Walken revealed details about his experiences dancing with Liza Minnelli and meeting Judy Garland. This conversation shed light on Walken's extensive career that has spanned seven decades, transitioning from Broadway to Hollywood. His reflections offer a glimpse into the golden age of show business and highlight the enduring impact of musicals on his development as an actor.
A Glimpse into Hollywood’s Golden Age
On January 16th, during a lively discussion on SiriusXM’s Town Hall, Christopher Walken, now 81, revisited memories from his formative years in the entertainment world. Host Andy Cohen, aged 56, inquired about Walken's experience dancing with Liza Minnelli when she was just 16. The event took place in 1962 during an Off-Broadway production of Best Foot Forward. Walken fondly recalled this moment, emphasizing Minnelli's undeniable talent even at such a young age.
The conversation then turned to Judy Garland, Minnelli's mother. Walken confirmed attending Minnelli’s sweet 16th birthday party, where he had the opportunity to dance with Garland herself. He described her as both a graceful dancer and strikingly beautiful. These interactions provided a vivid snapshot of Hollywood's glamorous past, connecting Walken’s early career with legendary stars.
Walken's journey began in the 1950s as a child actor under the name Ronnie Walken. By the 1960s, he adopted the stage name Christopher and embarked on a diverse acting career. From Broadway musicals to Hollywood blockbusters, Walken has showcased his versatility across various mediums. Notably, he won an Oscar in 2003 for his role in Catch Me If You Can.
Reflections on a Seven-Decade Career
Reflecting on his long-standing career, Walken expressed a deep appreciation for the craft of acting. In 2022, he told The New York Times that despite not having children or engaging in conventional hobbies like golf, his life has been enriched by his dedication to acting. Married for over five decades, Walken finds fulfillment in the roles he continues to take on.
His approach to acting is characterized by a playful spirit. Walken admitted to occasionally infusing his performances with humor, sometimes portraying characters inspired by Elvis, Bugs Bunny, or a U-boat commander. This whimsical attitude underscores his passion for the art form and his willingness to embrace the unexpected.
Ultimately, Walken views acting as a lifelong pursuit. “They say you don’t retire from acting — they retire you,” he once remarked. For Walken, the thrill of performing remains unwavering, driving him to continue entertaining audiences well into his eighth decade.
From these insights, it becomes clear that Walken's enduring legacy is built not only on his remarkable talent but also on his profound love for the craft. His reflections remind us of the timeless allure of Hollywood and the lasting impact of those who shaped its history.
The upcoming inauguration of President-elect Donald Trump has faced an unexpected change in venue. Originally planned for the National Mall, the ceremony will now take place inside the United States Capitol Rotunda due to severe weather forecasts. The National Weather Service predicts extremely low temperatures and a significant wind chill, prompting Trump to prioritize attendee safety. This marks only the third time in history that an inauguration has been moved indoors, following precedents set by Presidents Ronald Reagan and James Monroe. Trump also announced alternative arrangements for supporters, including a livestream viewing at the Capital One Arena.
Historical Precedent: Indoor Inaugurations in Extreme Weather
Severe weather conditions have occasionally forced presidential inaugurations indoors. On January 20, 2024, Donald Trump’s inauguration will join this rare list. The decision was made after meteorologists forecasted dangerously cold temperatures and strong winds, posing potential health risks to attendees. Historical records show that such measures have been taken before, notably when Ronald Reagan began his second term in 1985 amidst sub-zero wind chills. Similarly, James Monroe held his second inauguration inside the Capitol during a snowstorm in 1821. These instances underscore the importance of public safety over tradition.
Inaugural ceremonies are typically grand events held outdoors to accommodate large crowds. However, when faced with extreme weather, indoor venues become necessary. For Trump's inauguration, the Capitol Rotunda offers a secure and temperature-controlled environment. This space, recently used for honoring former President Jimmy Carter, is enclosed and protected from the elements. By moving the event indoors, Trump ensures that participants can witness the historic moment without risking their health. Additionally, he has arranged for fans to watch a live broadcast at the Capital One Arena, maintaining engagement with supporters who cannot be present in person.
Ensuring Public Safety and Engagement
Public safety remains a top priority for the Trump administration as they prepare for the inauguration. With temperatures expected to plummet, the decision to relocate the event indoors was made to prevent any harm to attendees. The Capitol Rotunda provides a controlled environment that shields participants from harsh weather conditions. This move not only protects those present but also honors historical practices when weather interferes with outdoor plans. Moreover, Trump has ensured that supporters can still participate by setting up a viewing area at the Capital One Arena.
The relocation of the inauguration addresses concerns about crowd exposure to dangerous weather. Trump, known for his attention to audience size, has found a way to balance safety and visibility. While the National Mall will remain empty of spectators, the Capital One Arena will host a live stream of the ceremony. Afterward, Trump plans to visit the arena, ensuring direct interaction with supporters. This arrangement reflects a thoughtful approach to managing a significant national event under challenging circumstances. By prioritizing safety and providing alternative viewing options, Trump aims to create a memorable inauguration experience for all involved.